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Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium

Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li

Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 330-335 doi: 10.1007/s11684-016-0459-6

Abstract:

The enhancer of zeste 2 polycomb repressive complex 2 subunit (Ezh2) is a histone-lysine N-methyltransferase

Keywords： polycomb repressive complex Ezh2 expression inner ear cochlea development

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Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 231-241 doi: 10.1007/s11684-013-0253-7

Abstract: Emerging data suggest that deregulation of polycomb group (PcG) proteins, which are key chromatin modifiersPcG proteins assemble into polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2

Keywords： liver cancer epigenetics histone modifications polycomb group proteins enhancer of zeste homolog 2 (EZH2

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GID complex regulates the differentiation of neural stem cells by destabilizing TET2

Frontiers of Medicine doi: 10.1007/s11684-023-1007-9

Abstract: interacts with the core subunits of the glucose-induced degradation-deficient (GID) ubiquitin ligase complex, an evolutionarily conserved ubiquitin ligase complex and is ubiquitinated by itself.The protein levels of GID complex subunits increased reciprocally with TET2 level upon NSC differentiationThe silencing of the core subunits of the GID complex, including WDR26 and ARMC8, attenuated the ubiquitinationOur results illustrated that the GID complex negatively regulates TET2 protein stability, further modulates

Keywords： TET2 GID complex neural stem cells differentiation of neurons

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Footholds optimization for legged robots walking on complex terrain

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11465-022-0742-y

Abstract: novel continuous footholds optimization method for legged robots to expand their walking ability on complexslipping or tripping on the edge of obstacles, and to improve its stability and safety when walking on compleximplemented the algorithm on a hexapod robot, and verified its feasibility in a walking experiment on a complex

Keywords： footholds optimization legged robot complex terrain adapting hexapod robot locomotion control

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Special issue: Reliability management of complex system

Frontiers of Engineering Management 2021, Volume 8, Issue 4, Pages 477-479 doi: 10.1007/s42524-021-0175-z

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Independent cover meshless particle method for complex geotechnical engineering

Jianqiu WU, Yongchang CAI

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 4, Pages 515-526 doi: 10.1007/s11709-017-0428-4

Abstract: A new Independent Cover Meshless Particle (ICMP) method is proposed for the analysis of complex geotechnicalsimple formulation and a low computational cost, and is easy for the numerical analysis and modeling of complex

Keywords： meshless method particle method independent cover CTM geotechnical engineering

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Forecast method for used number of parts and components based on complex network

LIU Fu-yun, QI Guo-ning, YANG Qing-hai

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 4, Pages 479-484 doi: 10.1007/s11465-006-0064-5

Abstract: Applying directed complex network to model the main structure of a product family, according to in-degree

Keywords： complex network industrial component analytic expression forecast

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Cationic organobismuth complex as an effective catalyst for conversion of CO

Xiaowen ZHANG, Weili DAI, Shuangfeng YIN, Shenglian LUO, Chak-Tong AU

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 1, Pages 32-37 doi: 10.1007/s11783-008-0068-y

Abstract: valuable chemicals, and to exploit new applications of organobismuth compounds, cationic organobismuth complex

Keywords： cationic organobismuth complex terminal epoxide carbon dioxide coupling cyclic carbonate

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Amino acid promoted hydrogen battery system using Mn-pincer complex for reversible CO hydrogenation to

Frontiers in Energy 2022, Volume 16, Issue 5, Pages 697-699 doi: 10.1007/s11708-022-0843-7

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Redox reactions of iron and manganese oxides in complex systems

Jianzhi Huang, Huichun Zhang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1255-8

Abstract: . • Oxidative reactions of Mn- and Fe-oxides in complex systems were reviewed. • Reductive reaction ofFe(II)/iron oxides in complex systems was examined. • Future research on examining the redox reactivityin complex systems was suggested.Due to experimental and analytical challenges associated with complex environments, there has been aTo bridge the gap between simple model systems and complex environmental systems, it is necessary to

Keywords： Iron oxides manganese oxides reduction oxidation complex systems reaction kinetics and mechanisms

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A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 12, Pages 1088-1098 doi: 10.1631/FITEE.1500111

Abstract: This technique is used in the driving circuit based on complex programmable logic devices (CPLDs), and

Keywords： Driving pulse edge modulation Switching voltage spike Complex programmable logic device (CPLD) Active

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Percolation-based health management of complex traffic systems

Frontiers of Engineering Management 2021, Volume 8, Issue 4, Pages 557-571 doi: 10.1007/s42524-021-0174-0

Abstract: of systems by reducing uncertain risks and cascading failures during their lifetime, is proposed for complex

Keywords： traffic health health management critical infrastructure systems science and engineering

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Research Efforts and Fruits of Complex Engineering Management

Ji-Shan He

Frontiers of Engineering Management 2015, Volume 2, Issue 1, Pages 1-1 doi: 10.15302/J-FEM-2015001

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Multiple damage detection in complex bridges based on strain energy extracted from single point measurement

Alireza ARABHA NAJAFABADI, Farhad DANESHJOO, Hamid Reza AHMADI

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 3, Pages 722-730 doi: 10.1007/s11709-020-0624-5

Abstract: The use of modal-based methods to identify damage in complex bridges is always associated with problems

Keywords： damage detection strain energy influence line complex bridges rotation displacement

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Systems Engineering in Large Complex Technical Projects

Guo Baozhu

Strategic Study of CAE 2008, Volume 10, Issue 3, Pages 25-30

Abstract:

Large complex technical programs/projects mainly involve the engineeringseems to be a confusion of "what systems engineering is" .The organization system is an open complex

Keywords： large complex technical projects systems engineering open complex giant system organizational creativity